Corpus of Electronic Texts Edition
An Irish Version of Gualterus de Dosibus (Author: Walter de Agilon/Galterius Agilinus)

paragraph 26

Dosage determined from compounding the medicine: let it be varied, for should there be a compound in which there are contrary ingredients, one of which ingredients diminishes the efficacy of the other, it is necessary to put much of the efficacious and little of the harmful medicine into it. These are the conditions for the dosage of the simples which are put into the composites, and it is in accordance with these conditions we prescribe what follows.

Note, that the conditions to be observed are the same in the doses of the simples and in the doses of the composites. Note also that some of the laxatives are uncompounded and others are compounded.