Corpus of Electronic Texts Edition
An Irish Version of Gualterus de Dosibus (Author: Walter de Agilon/Galterius Agilinus)

paragraph 11

Let the medicine indeed be compounded in accordance with the remoteness of the location for it is obvious, should the affected part be far away from the stomach where the medicine is first received, it is necessary for the medicine to be compounded so that it is not very much weakened by the distance to the extent it would not be possible for it to penetrate as far as the member. For that reason eastern saffron is put into the medicines, since it causes them to penetrate swiftly and easily to the members.