Let the medicines be compounded according to the extent of the diseases of similar and dissimilar evil complexions, as is plain when a bad hot or cold complexion of the body is found together with some quantity which cannot be changed by a single simple only. For that reason it is necessary to make from different simples, used in the same proportions, a single composite medicine which can combat with the quantity of the evil complexion of the body. For example, should the body be of an immoderately high temperature of the second degree, and should no contrary cold simple of the same degree be procured let two simples be procured, i.e. a hot medicine of the first degree and a cold medicine of the third degree. When these are mixed and compounded in this way they will be cold in the second degree.