If the smalipox be caused by sanguine humour, the pustules are pointed on top and broad below, ripen at once, and escape through running;730 the which is a sign of health; for sanguine humour is the cause thereof, and it is subject to the digestion and is a friend of nature.731 If the complexion be hot and moist and the wind south in spring, it is certain that it comes from red blood.