Item all imposthumes occur more frequently in winter, than at any other time, and remain longer, and if they be relieved they do not come back again, as Hippocrates says in the third book of Prognostica; and it is of the imposthumes occurring in crisis,427 caused by cold humours, that he speaks; for those humours are more numerous in winter, and it is then these imposthumes are most frequent and most plentiful.